Kidney Disease and cats

You may have heard of kidney disease and cats and how common it is. In this week’s blog I break it down.

What do kidneys do?

Kidneys filter waste from the body, produce urine and assist in normal blood pressure amongst other things

How is it diagnosed?

Blood examination from blood tests and urinalysis (checking urine from a urine sample). An increase in  creatinine of the bloods is checked. Creatinine is a waste product that is filtered out by healthy kidneys.   A vet may perform a cystocentesis where they take urine directly from the bladder or non absorbent cat litter such as this may be an option. speak to your vet. Obviously if you live in a home with more than one cat you need to know who’s urine is who’s. Urine can also be checked for bacteria and crystals too.

What are the signs and symptoms?

Symptoms can include drinking more, weight loss and vomiting as well as urinating more. In the initial stages symptoms may be subtle. High blood pressure can lead to blindness. It is common in older cats, that’s why If a cat is 10 years and older it is recommended that they go to the vets twice per year and screening should start from age 7. 

Other conditions such as the below may develop or exacerbate chronic kidney disease (Taylor et., al 2026): 

  • Hyperthyroidism – symptoms can include a dull coat, weight loss, increase in thirst and eating

  • Excess blood proteins  - found during blood and urine analysis following a urine challenge such as blood in the urine and small amounts 

  • Ureteral obstructions  - symptoms such as vomiting, abdominal pain, straining in the litter tray

  • Calcium stones can be caused by diet changes, and risk factors included neutered males, and those who are obese. 

Is there any information on breeds to be aware of?

38 % of Persian cats worldwide have an inherited disease- Autosomal dominant polycystic kidney disease. There a genetic tests available so that these cats are no bred from https://www.langfordvets.co.uk/diagnostic-laboratories/cat-genetic-testing/genetic-disease-and-trait-tests/polycystic-kidney-disease/


What treatment options are there?


If you’d like to read more here are some useful websites and books

https://icatcare.org/resources/cat-carer-guide-managing-chronic-kidney-disease-in-cats.pdf

2026 iCatCare consensus guidelines on the diagnosis and management of chronic kidney disease in cats

https://journals.sagepub.com/doi/10.1177/1098612X261466553

Sarah Caney, Caring for a cat with chronic kidney disease

https://www.vetprofessionals.com/store/products_detail?ProductName=Caring-for-a-cat-with-chronic-kidney-disease-(4th-edition)

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Neutering – things to think about